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Drug and Alcohol Testing Branton TX - (800) 828-7086

DOT 300x183Our local DOT drug and alcohol testing centers are located in Branton TX and the surrounding areas providing DOT drug testing, DOT alcohol testing and DOT physicals for all DOT modes regulated by Part 40. Same day service is available at our Branton TX DOT drug testing facilities and most of our DOT drug testing locations are within minutes of your home or office.

What type of DOT Testing is required?

Coastal Drug Testing provides DOT pre-employment, random, post-accident, reasonable suspicion and return to duty testing at our Branton TX DOT drug testing centers.

If you hold a CDL license, a large, medium or a small trucking company, Coastal Drug Testing has a complete DOT compliance package which includes all the requirements to comply with CFR 49 part 40.

All Coastal Drug Testing DOT drug testing centers utilize SAMHSA Certified laboratories and a licensed Medical Review Officer as required by DOT part 40 regulations.

The U.S Department of Transportation (DOT) requires that all DOT regulated "safety sensitive" employees have a negative DOT pre-employment drug test result on file and be actively enrolled in a DOT approved random drug and alcohol random testing pool (consortium).

In addition, if a DOT regulated company has more than one "safety sensitive" employee, the employer must also have a written DOT drug and alcohol policy along with an on-site supervisor that must have completed a reasonable suspicion supervisor training program.

On the road and need a DOT Drug or Alcohol test? No Worries!

To be compliant with DOT regulations, a company's DOT drug and alcohol testing program must have the following components:

  • Employee Drug Testing
  • Written Drug and Alcohol Policy
  • Supervisor Training
  • Substance Abuse Referral
  • Employee Education
  • Random Selection Program
  • Post Accident Testing
  • Designated Employer Representative
  • Federal Chain of Custody Forms
  • Part 40 Regulations on File

The Department of Transportation (DOT) has specific drug and alcohol testing requirements for the all transportation modes all DOT agencies.

Our modes included are:

  • Federal Motor Carrier Safety Administration (FMCSA)
  • Federal Aviation Administration (FAA)
  • Federal Transit Administration (FTA)
  • United States Coast Guard (USCG)
  • Pipeline and Hazardous Materials Safety Administration (PHMSA)
  • Federal Railroad Administration (FRA)

Are You Enrolled in a DOT Consortium?

Individuals who are employed in a position designated as "safety sensitive" must be actively enrolled in a random drug and alcohol testing program. Oftentimes, covered employees will join a group of other DOT regulated employees in a random testing program and this is referred to as a DOT Consortium. Generally, an employer who has less than fifty employees or single operators will join the consortium which will comply with the random drug and alcohol testing requirements of 49 CFR Part 40. Employers that have over 50 employees who are regulated by Part 40 may elect to be enrolled in a "stand alone" random testing pool.

The DOT consortium is cost effective and complies with all requirements of 49 CFR Part 40 which mandates that all "safety sensitive" employees be enrolled in a random drug and alcohol testing program.

The Department of Transportation (DOT) has strict regulations requiring regulated companies and independent operators (CDL License Holders) to be an active member of a DOT drug and alcohol Consortium and failure to comply with these regulations can result in significant fines and other DOT sanctions.

We are fully versed in the DOT procedures for pre-employment drug testing, random drug testing, reasonable suspicion drug testing, post-accident drug testing, return to duty drug testing and follow up drug testing.

DOT regulated companies with multiple safety sensitive employees must also have an employee within the company who is assigned as the "designated employer representative" (DER). This is the person responsible for removing any DOT "safety sensitive" employee who is covered by 49 CFR Part 40 from performing a DOT safety sensitive position when a positive drug or alcohol test result has occurred or an employee has refused to take a required DOT test.

If you have recently become a DOT regulated company, within the next 18 months the Department of Transportation (DOT) will conduct a "new entrant" inspection to ensure that you are in compliance with all DOT regulations including the drug and alcohol testing requirements. If you are currently a DOT regulated company, you are subject to regular inspections to ensure compliance.

Avoid DOT fines, penalties and be complaint with all DOT drug and alcohol testing regulations! Coastal Drug Testing can assist small, medium and large DOT companies in complying with all requirements of 49 CFR Part 40.

DOT Drug Testing Locations in Branton TX

1510 HIGHWAY 206 14.9 miles

1510 HIGHWAY 206
CISCO, TX 76437
Categories: CISCO TX

304 S DAUGHERTY AVE 18.0 miles

304 S DAUGHERTY AVE
EASTLAND, TX 76448
Categories: EASTLAND TX

(Don't see a location near you? Call us (800) 828-7086)

Local Area Info: Staphylococcus aureus alpha toxin

Alpha-toxin, also known as alpha-hemolysin (Hla), is the major cytotoxic agent released by bacterium Staphylococcus aureus and the first identified member of the pore forming beta-barrel toxin family. This toxin consists mostly of beta-sheets (68%) with only about 10% alpha-helices. The hla gene on the S. aureus chromosome encodes the 293 residue protein monomer, which forms heptameric units on the cellular membrane to form a complete beta-barrel pore. This structure allows the toxin to perform its major function, development of pores in the cellular membrane, eventually causing cell death.

Alpha-toxin has been shown to play a role in pathogenesis of disease, as hla knockout strains show reductions in invasiveness and virulence. The dosage of toxin can result in two different modes of activity. Low concentrations of toxin bind to specific, but unidentified, cell surface receptors and form the heptameric pores. This pore allows the exchange of monovalent ions, resulting in DNA fragmentation and eventually apoptosis. Higher concentrations result in the toxin absorbing nonspecifically to the lipid bilayer and forming large, Ca2+ permissive pores. This in turn results in massive necrosis and other secondary cellular reactions triggered by the uncontrolled Ca2+ influx.

The structure of the protein has been solved by X-ray crystallography and is deposited in the PDB as id code 7ahl. Seven monomers each contribute a long beta-hairpin to a fourteen stranded beta barrel that forms a pore in the cell membrane. This pore is 14 Ångström wide at its narrowest point. This width equals the diameter of approximately 4 calcium ions.

DATE TIME: 09-27-2024 11:34am Fri